Comprehensive Guide to Antidepressants: Side Effects Chart Explained

Mia Nightshade

Updated Thursday, September 5, 2024 at 12:00 AM CDT

Navigating the world of antidepressants can be overwhelming, especially when considering the potential side effects. The "Antidepressants Side Effects Chart" offers a detailed breakdown of various antidepressants and their associated side effects across multiple categories. Here is a comprehensive guide to understanding this chart and its implications for individuals considering or currently taking these medications.

The chart lists 14 common antidepressants, each evaluated for side effects such as Sexual Dysfunction, Gastrointestinal Discomfort, Weight Gain, QTc Prolongation, Hypotension, Insomnia, and Drowsiness. The side effects are graded on a scale from 0 (None) to 4 (High), providing a clear visual representation of the risks associated with each medication.

### Antidepressants Listed:

1. S*********

2. Paroxetine

3. C*********

4. Esc*********

5. F*********

6. Fluvoxamine

7. Vortioxetine

8. T********

9. B********

10. V**********

11. D*********

12. Mirtazapine

13. Agomelatine

14. Amitriptyline

### Key Insights:

- **Sexual Dysfunction**: Many users have reported varying degrees of sexual dysfunction. For instance, Esc********* has been highlighted for causing mild erectile dysfunction but also boosting confidence in social situations.

- **Gastrointestinal Discomfort**: SSRIs and SNRIs often cause gastrointestinal side effects that typically subside within the first weeks of treatment.

- **Weight Gain**: Some antidepressants are notorious for causing weight gain. Users have noted that medications like Mirtazapine can lead to significant weight changes.

- **QTc Prolongation**: This refers to the impact on heart rhythm. Amitriptyline, among others, has been flagged for increasing QTc prolongation, which may be a concern for those with existing heart conditions.

- **Hypotension**: The risk of low blood pressure varies, with some medications posing a higher risk than others.

- **Insomnia**: Certain antidepressants, like F*********, may induce insomnia, while others like T******** are noted for causing drowsiness and are sometimes used off-label as sleep aids.

- **Drowsiness**: Medications such as T******** and Mirtazapine are often associated with high levels of drowsiness, making them suitable for nighttime use.

### User Experiences:

- One user mentioned using T******** as a sleep aid due to its sedating effects, likening it to first-generation allergy medications that induce sleep.

- Another user found Wellbutrin (B********) effective, summarizing it with "Wellbutrin FTW!"

- A user shared their experience with non-stimulant ADHD meds like Qelbree, noting an improvement in mood and anxiety, despite initial side effects like nausea and constipation.

- Concerns were raised about the accuracy of the chart, with one user pointing out that Duloxtine's drowsiness rating seemed incorrect based on personal experience.

- Users also discussed potential off-label benefits and side effects of various medications, such as increased libido with Vivactil (Protriptyline Hydrochloride) and vivid dreams with T********.

### Important Considerations:

- Side effects from antidepressants are highly individualized. This chart represents the general population's risk but may not predict individual experiences accurately.

- It's crucial to consult healthcare providers when considering antidepressants, especially for those with pre-existing conditions or concerns about specific side effects.

- Patience is key when finding the right medication. As one user noted, the journey to find an effective antidepressant can be challenging but is ultimately worthwhile.

### Conclusion:

The "Antidepressants Side Effects Chart" is a valuable resource for individuals and healthcare providers navigating the complex landscape of antidepressant medications. By understanding the potential side effects and sharing personal experiences, users can make informed decisions and find the most suitable treatment for their needs. Always consult a medical professional before making any changes to medication regimens. For more detailed information, visit the source: [uptodate.com](https://www.uptodate.com).

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View source: Imgur

Top Comments from Imgur

EdelwoodHikes

G*****mit, science, give us a 0-0-0-0-0-0-0, and give it now!

TiredSnowball

Fun fact: t******** is sometimes used as a sleep aid instead of anti-depressant as it knocks people out quickly and last less in the system vs some other prescription sleep aids. It's a first gen antidepressant, and similarly to first gen allergy meds, just puts most people to sleep.

JerzeeTomato

Wellbutrin FTW!

notacobra

I don't really agree with this chart. First, while it gives the disclaimer that side effects are highly personalised, it's still a gross oversimplification - given the massively varied responses and metabolism of these drugs (and each of their classes). Second, there's a bunch of mistakes. Like d********* with a 0 for drowsiness being one of the MOST sedating SNRIs - even legally requiring a sedation warning in Australia.

nomorehate

The non-stim ADHD meds my Dr. prescribed have been used off label for anxiety & depression. 1 month in, and while I'm not tripping over rainbows, I have noticed an improvement in my mood and overall anxiety. It cuts away a lot of the dread of starting a task, which I feel is a HUGE factor in my adhd/depr/anx. Exec.function is still a hit-or-miss, but side effects wise (if you can handle a week straight of nausea then constipation) I think Qelbree is worth trying!

relsky

What is QTc prolongation?

YeastInfectedWhiskerBiscuit

Also, VIVACTIL AKA (PROTRIPTYLINE HYDROCHLORIDE) increases your libido. I was on the stuff for a year. Was constantly H**ny and much, MUCH, more sensitive..Just in case anyone is looking for something that isn't as much of a sexual downer like most other antidepressants.

wildwestpb

Well, this is worrisome. I’m on amitriptyline and have heart problems already. Wonder if I’ll be changing meds on my next checkup.

Arathius8

I always used to tell people it takes around a year to find an antidepressant that works and to try and be patient. Then I started a search of my own and I never realized what a nightmare the process is. I have tried F*********, D********* and Esc********* and each has made me feel worse than I felt before my search began. It can be very disheartening.

JohnBluehill

Esc********* both gave me the confidence to date and some mild ED. Yayyyyyy! I'm actually not that mad. I think it's f***ing hilarious.

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